SAB5701747

Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit

• UNSPSCコード: 12352203
• NACRES: NA.41
• クローン: polyclonal
• application: WB
• 化学種の反応性: mouse, rat, human
• テクニック: western blot: 1:500-1:2000

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: liquid
• 化学種の反応性: mouse, rat, human
• 濃度: 1.59 mg/mL
• テクニック: western blot: 1:500-1:2000
• UniProtアクセッション番号: P19174
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr783)
• 遺伝子情報: human ... PLCG1(5335)

詳細

詳細

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding Y783 of human PLC gamma 1 (PLCG1)

物理的形状

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable