SAB5700472

Anti-Phospho-PLCG2-Y1217 antibody produced in rabbit

• 別名: APLAID, FCAS3, PLC-IV, PLC-gamma-2, PLCG2
• UNSPSCコード: 12352203

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 147
• 化学種の反応性: mouse, human
• 濃度: 0.37 mg/ml
• テクニック: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProtアクセッション番号: P16885
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr1217)
• 遺伝子情報: human ... PLCG2(5336)

詳細

詳細

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

免疫原

A synthetic phosphorylated peptide around Y1217 of human PLCG2 (NP_002652.2).

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable