SAB5700007

Anti-TCF3 antibody produced in rabbit

• 別名: AGM8, E2A, E47, ITF1, TCF-3, TCF3, VDIR, bHLHb21
• UNSPSCコード: 12352203
• NACRES: NA.41
• クローン: polyclonal
• application: WB
• 化学種の反応性: human, mouse, rat
• テクニック: western blot: 1:500-1:2000

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 67; 68
• 化学種の反応性: human, mouse, rat
• 濃度: 4.64mg/ml
• テクニック: western blot: 1:500-1:2000
• UniProtアクセッション番号: P15923
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TCF3(6929)

詳細

詳細

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

免疫原

Recombinant protein of human TCF3

物理的形状

PBS with 0.02% sodium azide,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable