SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• 別名: NGFR, TNFRSF16, p75NGFR, p75NTR
• UNSPSCコード: 12352203

特性

• 結合体: unconjugated
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: NGFR5, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human, ( Non-human primates), ( Rabbit), ( Cat)
• 濃度: 1 mg/ml
• テクニック: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• アイソタイプ: IgG1
• UniProtアクセッション番号: P08138
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NGFR(4804)

詳細

詳細

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

特異性

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

免疫原

Purified CD271 protein isolated from human melanoma cell line A875

物理的形状

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

調製ノート

Purified by protein-A affinity chromatography.

保管および安定性

Store at 2-8°C. Do not freeze.

その他情報

The antibody solution should be gently mixed before use.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable