SAB4702067

Monoclonal Anti-CD138 APC produced in mouse

• 別名: SDC, SYND1, syndecan 1
• UNSPSCコード: 12352203

特性

• 結合体: Allophycocyanin conjugate
• 品質水準: 100
• 抗体製品タイプ: primary antibodies
• クローン: MI15, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: ( Human), ( Non-human primates), rat
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• UniProtアクセッション番号: P18827
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SDC1(6382)

詳細

詳細

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

特異性

The mouse monoclonal antibody MI15 recognizes an extracellular epitope of CD138 (syndecan 1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.

免疫原

A mixture of U266 and XG-1 human myeloma cell lines

物理的形状

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

調製ノート

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

保管および安定性

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

その他情報

The antibody solution should be gently mixed before use.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable