SAB4504373

Anti-phospho-Cortactin (pTyr⁴⁶⁶) antibody produced in rabbit

affinity isolated antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 61 kDa
• 化学種の反応性: human, rat, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: Q60598
• UniProtアクセッション番号: Q14247
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr466)
• 遺伝子情報: mouse ... Cttn(13043)

詳細

詳細

Cortactin is an actin-related protein 2/3 (Arp2/3) complex–activating and filamentous (F)-actin–binding protein. This protein is coded by CTTN gene that maps to human chromosome 11q13.

免疫原

The antiserum was produced against synthesized peptide derived from mouse Cortactin around the phosphorylation site of Tyr466.

Immunogen Range: 441-490

アプリケーション

Anti-phospho-Cortactin (pTyr421) antibody has been used in western blotting and immunoprecipitation.

生物化学的／生理学的作用

Cortactin controls Arp2/3-mediated actin polymerization. This protein also modulates aggressive cancer cell traits like tumor growth, cancer cell invasion and motility, and serum and anchorage-independent growth.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable