SAB4504371

Anti-phospho-Connexin 43 (pSer³⁶⁸) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-AVSD3, Anti-CMDR, Anti-CX43, Anti-EKVP, Anti-EKVP3, Anti-GJAL, Anti-HLHS1, Anti-HSS, Anti-ODDD, Anti-PPKCA
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 43 kDa
• 化学種の反応性: human, rat, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: P17302
• UniProtアクセッション番号: P17302
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer368)
• 遺伝子情報: human ... GJA1(2697)

詳細

詳細

Connexin 43 (Cx43) is also known as GJA1 (gap junction protein alpha 1) and belongs to a large family of homologous connexin proteins. This protein has an intracellular N-terminus, four transmembrane domains, two extracellular loops, one cytoplasmic loop and an intracellular C-terminus. It is located on human chromosome 6q22-q23.

免疫原

The antiserum was produced against synthesized peptide derived from human Connexin 43 around the phosphorylation site of Ser368.

Immunogen Range: 332-381

生物化学的／生理学的作用

Connexin 43 participates in the multiplication and differentiation of mature T cells. This protein also participates in the secretion and manufacturing of cytokines. Mutations in connexin 43 (Cx43) gene result in pleiotropic phenotype of oculodentodigital dysplasia. CX43 helps to release lactate from glycolytic pancreatic ductal adenocarcinoma cells.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable