SAB4503894

Anti-phospho-Arrestin 1 (pSer⁴¹²) antibody produced in rabbit

affinity isolated antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 47 kDa
• 化学種の反応性: rat, human, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: P49407
• UniProtアクセッション番号: P49407
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer412)
• 遺伝子情報: human ... ARRB1(408)

詳細

詳細

Arrestin 1 (ARRB1) is also termed as β-arrestin-1. This is a cytoplasmic adaptor protein located on human chromosome 11q13.

免疫原

The antiserum was produced against synthesized peptide derived from human Arrestin 1 around the phosphorylation site of Ser412.

Immunogen Range: 369-418

生物化学的／生理学的作用

Arrestin 1 (ARRB1) participates in DNA damage accumulation and cell apoptosis. Deletion of ARRB1 blocks DDR (DNA damage response) pathway activation. During hypoxia, ARRB1 controls breast cancer cell survival with the help of HIF-1 transcription factor. This gene can act as a scaffold and an adaptor in receptor endocytosis and signal transduction.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable