おすすめの製品
由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 64 kDa
化学種の反応性
human
濃度
~1 mg/mL
テクニック
ELISA: 1:20000
western blot: 1:500-1:1000
NCBIアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SLC24A6(80024)
詳細
The SLC24A6 (solute carrier family 8 member B1) gene is mapped to human chromosome 12q24.13. The gene codes for a K+-dependent Na+/Ca2+ exchanger. The encoded protein is ubiquitously expressed in all the tissues. It is localized to inner mitochondrial membrane.
免疫原
The antiserum was produced against synthesized peptide derived from human SLC24A6.
Immunogen Range: 494-543
Immunogen Range: 494-543
生物化学的/生理学的作用
SLC24A6 (solute carrier family 8 member B1) protein is responsible for maintaining Ca2+ homeostasis in the cell. SLC24A6 protein regulates sodium uptake and calcium efflux from the mitochondria.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Transporters in Drug Discovery and Development: (2014)
Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6.
The Journal of Biological Chemistry, 279(7), 5867- 5876 (2004)
NCLX Protein, but Not LETM1, Mediates Mitochondrial Ca2+ Extrusion, Thereby Limiting Ca2+-induced NAD(P)H Production and Modulating Matrix Redox State*
The Journal of Biological Chemistry, 289(29), 20377-20385 (2014)
Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception.
Biochimica et Biophysica Acta, 1863(12), 2868-2880 (2016)
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