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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 60 kDa
化学種の反応性
human, rat, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... RELA(5970)
詳細
Anti-NF-κB p65 Antibody detects endogenous levels of total NF-κB p65 protein.
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A), also known as nuclear factor κ-B (NF-κ-B) p65 subunit, codes for an important constituent of the NF-κB complex. The gene encoding it is localized on human chromosome 11q13.1. It is also referred as nuclear factor κB subunit 3 (NFκB3).
免疫原
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.
Immunogen Range: 247-296
Immunogen Range: 247-296
アプリケーション
Anti-NF-κB p65 antibody produced in rabbit is used in Western Blotting.
生物化学的／生理学的作用
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) or nuclear factor NF-κ-B p65 subunit participates in the nuclear factor κ-B (NFκB) signaling pathway. It also modulates inflammation. Alterations in the gene have been linked to schizophrenia and startle reactions.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Reversal of cardiac and skeletal manifestations of Duchenne muscular dystrophy by cardiosphere-derived cells and their exosomes in mdx dystrophic mice and in human Duchenne cardiomyocytes.
Aminzadeh MA, et al.
bioRxiv, 128900-128900 (2017)
Bone morphogenetic protein-2 exhibits therapeutic benefits for osteonecrosis of the femoral head through induction of cartilage and bone cells.
Wang C, et al.
Experimental and Therapeutic Medicine (2018)
Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
Pare G, et al.
PLoS Genetics, 7(4), e1001374-e1001374 (2011)
Variants of the RELA gene are associated with schizophrenia and their startle responses.
Hashimoto R, et al.
Neuropsychopharmacology, 36(9), 1921-1921 (2011)
Siwei Tan et al.
Cell death & disease, 12(5), 474-474 (2021-05-14)
Fas/Fas ligand (FasL)-mediated cell apoptosis involves a variety of physiological and pathological processes including chronic hepatic diseases, and hepatocytes apoptosis contributes to the development of liver fibrosis following various causes. However, the mechanism of the Fas/FasL signaling and hepatocytes apoptosis
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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