おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 51 kDa
化学種の反応性
mouse, human, rat
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KRT14(3861)
詳細
Anti-Keratin 14 Antibody detects endogenous levels of total Keratin 14 protein.
CK14/ KRT14 (keratin 14) is one of the cytokeratin isotypes of human cells. It is the intermediate filament protein, which is the feature of epithelial cells. It is located in human chromosome 17q21.
CK14/ KRT14 (keratin 14) is one of the cytokeratin isotypes of human cells. It is the intermediate filament protein, which is the feature of epithelial cells. It is located in human chromosome 17q21.
免疫原
The antiserum was produced against synthesized peptide derived from human Keratin 14.
Immunogen Range: 1-50
Immunogen Range: 1-50
生物化学的／生理学的作用
CK14/ KRT14 (keratin 14) participates in the collective invasion of salivary adenoid cystic carcinoma (SACC). Mutations in KRT14 results in epidermolysis bullosa simplex.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
Maree Bilandzic et al.
Cancers, 11(9) (2019-08-25)
Epithelial ovarian cancer metastasis is driven by spheroids, which are heterogeneous cancer cell aggregates released from the primary tumour mass that passively disseminate throughout the peritoneal cavity to promote tumour spread, disease recurrence, and acquired chemoresistance. Despite their clinical importance
Cytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinoma.
Gao XL, et al.
PLoS ONE, 12(2), e0171341-e0171341 (2017)
KRT14 Haploinsufficiency Results in Increased Susceptibility of Keratinocytes to TNF-?-Induced Apoptosis and Causes Naegeli?Franceschetti?Jadassohn Syndrome.
Lugassy J, et al.
The Journal of Investigative Dermatology, 128(6), 1517-1524 (2008)
Mariaceleste Aragona et al.
Nature, 584(7820), 268-273 (2020-07-31)
The ability of the skin to grow in response to stretching has been exploited in reconstructive surgery1. Although the response of epidermal cells to stretching has been studied in vitro2,3, it remains unclear how mechanical forces affect their behaviour in
The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains.
Carlos Gomez-Diaz et al.
iScience, 24(11), 103241-103241 (2021-11-11)
The Linear Ubiquitin Chain Assembly Complex (LUBAC), composed of HOIP, HOIL-1L, and SHARPIN, promotes tumor necrosis factor (TNF)-dependent NF-κB signaling in diverse cell types. HOIL-1L contains an Npl4 Zinc Finger (NZF) domain that specifically recognizes linear ubiquitin chains, but its
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）