SAB4501488

Anti-GPR109 antibody produced in rabbit

affinity isolated antibody

• 別名: G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, GPR109B, Nicotinic acid receptor 2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 44 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBIアクセッション番号: P49019
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... HCAR3(8843)

詳細

詳細

Anti-GPR109 antibody detects endogenous levels of total GPR109 protein.

GPR109B (G-protein coupled receptor 109B) is also called as hydroxycarboxylic acid receptor 3 (HCA3) and HM74 (G-protein coupled receptor). It belongs to the subfamily of G-protein-coupled receptors (GPCR). GPR109B is expressed in adipose tissue, lung, spleen and peripheral blood leukocytes. It is mapped to human chromosome 12q24.31.

免疫原

The antiserum was produced against synthesized peptide derived from human GPR109.

Immunogen Range: 285-334

生物化学的／生理学的作用

GPR109B (G-protein coupled receptor 109B) helps to carry out the activities of D-Phe and D-Trp on neutrophils. HCA3 receptors helps to activate ERK1/2 through PTX (Pertussis toxin)-sensitive Gi (inhibitory G) protein-dependent pathway.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable