SAB4500466

Anti-CRHR2 antibody produced in rabbit

affinity isolated antibody

• 別名: CRF-R 2, CRF2, CRH-R 2, Corticotropin-releasing factor receptor 2, Corticotropin-releasing hormone receptor 2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 47 kDa
• 化学種の反応性: mouse, rat, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBIアクセッション番号: Q13324
• UniProtアクセッション番号: Q13324
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CRHR2(1395)

詳細

詳細

Anti-CRHR2 antibody detects endogenous levels of total CRHR2 protein.

The CRHR2 (corticotropin releasing hormone receptor 2) gene is a member of G protein coupled receptors (GPCRs) family. It is located on human chromosome 7p21-p15. It has 12 exons and approximately 50,000 base pairs (Kbp). It has 3 isoforms, such as CRHR2α β and γ out of which, CRHR2γ is mostly expressed in the brain and CRHR2α 2β are expressed in the brain and smooth muscle.

免疫原

The antiserum was produced against synthesized peptide derived from human CRHR2.

Immunogen Range: 71-120

アプリケーション

Anti-CRHR2 antibody has been used in immunoprecipitation and western blotting .{6,7}

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

生物化学的／生理学的作用

CRHR2 (corticotropin releasing hormone receptor 2) is involved in the relaxation of smooth muscle response and may affect the response of acute airway bronchodilator to short acting β2 agonist treatment of asthma. Signaling pathways of CRHR2 modulate the hypothalamic-pituitary-adrenocortical axis.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable