SAB4300668

Anti-Synpr antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-synaptophysin
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~37 kDa
• 交差性: mouse, human, rat
• 濃度: 1 mg/mL
• テクニック: western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (G-P-T-S-F)
• NCBIアクセッション番号: NM_023974.1
• UniProtアクセッション番号: Q8TBG9
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: rat ... Synpr(66030)

詳細

詳細

The antibody detects endogenous levels of total synaptophysin 2 protein.

免疫原

Peptide sequence around aa. 257-261 (G-P-T-S-F), according to the protein NP_076464.1

特徴および利点

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ターゲットの説明

Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable