SAB4300227

Anti-phospho-SNCA (pTyr¹³⁶) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗MGC110988抗体 ウサギ宿主抗体, 抗NACP抗体 ウサギ宿主抗体, 抗PARK1抗体 ウサギ宿主抗体, 抗PARK4抗体 ウサギ宿主抗体
• MDL番号: MFCD02095740
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~18 kDa
• 交差性: human, mouse, rat
• 濃度: 1 mg/mL
• テクニック: indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (Q-D-YP-E-P)
• NCBIアクセッション番号: NP_000336.1
• UniProtアクセッション番号: P37840
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr136)
• 遺伝子情報: human ... SNCA(6622)

詳細

免疫原

Peptide sequence around phosphorylation site of tyrosine 136 (Q-D-Y(p)-E-P), according to the protein SNCA.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

ターゲットの説明

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable