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Merck
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主要文書

安全性情報

SAB4300198

Sigma-Aldrich

Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit

affinity isolated antibody

別名:

Anti-JNK-55 antibody produced in rabbit, Anti-JNK2 antibody produced in rabbit, Anti-JNK2A antibody produced in rabbit, Anti-JNK2ALPHA antibody produced in rabbit, Anti-mitogen-activated protein kinase 9 antibody produced in rabbit

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About This Item

MDL番号:
MFCD02264074
UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

100

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

分子量

~46 kDa
 ~54 kDa

交差性

rat, human, mouse

濃度

1 mg/mL

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

アイソタイプ

IgG

免疫原配列

(M-M-TP-P-Y)

NCBIアクセッション番号

NP_001128516.1

UniProtアクセッション番号

P45984

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

phosphorylation (pThr183)

遺伝子情報

human ... MAPK9(5601)

免疫原

Peptide sequence around phosphorylation site of threonine 183 (M-M-T(p)-P-Y), according to the protein MAPK9.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

ターゲットの説明

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

SAB4300198-100UG:

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
951411249

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文書ライブラリにアクセスする

Kenta Niimi et al.
Biochemical and biophysical research communications, 489(4), 413-419 (2017-06-01)
Sprouting migration of lymphatic endothelial cell (LEC) is a pivotal step in lymphangiogenic process. However, its molecular mechanism remains unclear including effective migratory attractants. Meanwhile, forkhead transcription factor FOXO1 highly expresses in LEC nuclei, but its significance in LEC migratory
Manabu Inoue et al.
Scientific reports, 8(1), 6736-6736 (2018-05-02)
Immune responses to parasitic pathogens are affected by the host physiological condition. High-density lipoprotein (HDL) and low-density lipoprotein (LDL) are transporters of lipids between the liver and peripheral tissues, and modulate pro-inflammatory immune responses. Pathogenic mycobacteria are parasitic intracellular bacteria
Meraj A Khan et al.
Scientific reports, 7(1), 3409-3409 (2017-06-15)
Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established. We hypothesized that stress-activated protein kinase or c-Jun N-terminal Kinase (SAPK/JNK) is a molecular switch
Lilian Quero et al.
Arthritis research & therapy, 19(1), 245-245 (2017-11-04)
Toll-like receptors (TLRs) and macrophages play an important role in rheumatoid arthritis (RA). Currently, it is not clear whether inflammatory M1 or anti-inflammatory M2 predominate among the resident macrophages in the synovium. In the present study, we set out to
Lai Jiang et al.
Journal of neuroinflammation, 14(1), 174-174 (2017-09-02)
Activated astrocytes release matrix metalloproteinase-2/9 (MMP-2/9) to induce central sensitization and maintain neuropathic pain. However, the mechanisms involved in the activation of MMP-2/9 on astrocytes during pain remain poorly understood. Meanwhile, there is a lack of effective treatment to inhibit
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