SAB4300140

Anti-phospho-PRKCQ (pSer⁶⁹⁵) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-MGC126514 antibody produced in rabbit, Anti-MGC141919 antibody produced in rabbit, Anti-PRKCT antibody produced in rabbit, Anti-nPKC-theta antibody produced in rabbit, Anti-protein kinase C, theta antibody produced in rabbit
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~80 kDa
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• アイソタイプ: IgG
• 免疫原配列: (N-F-SP-F-M)
• NCBIアクセッション番号: NP_006248.1
• UniProtアクセッション番号: Q04759
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer695)
• 遺伝子情報: human ... PRKCQ(5588)

詳細

免疫原

Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M), according to the protein PRKCQ.

特徴および利点

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ターゲットの説明

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable