SAB4300105

Anti-phospho-HDAC8 (pSer³⁹) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗RPD3抗体 ウサギ宿主抗体
• MDL番号: MFCD02686596
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: IF; IHC (p)
• クローン: polyclonal
• 化学種の反応性: human
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~42 kDa
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• アイソタイプ: IgG
• 免疫原配列: (R-A-SP-M-V)
• NCBIアクセッション番号: NP_001159890.1
• UniProtアクセッション番号: Q9BY41
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer39)
• 遺伝子情報: human ... HDAC8(55869)

詳細

免疫原

Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V), according to the protein HDAC8.

特徴および利点

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ターゲットの説明

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable