SAB4300097

Anti-phospho-CDC25C (pSer²¹⁶) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-CDC25 antibody produced in rabbit, Anti-cell division cycle 25 homolog C (S. pombe) antibody produced in rabbit
• MDL番号: MFCD00802890
• UNSPSCコード: 12352203
• NACRES: NA.43
• 結合体: unconjugated
• application: IF; IHC (p)
• クローン: polyclonal
• 化学種の反応性: human
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~60 kDa
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• アイソタイプ: IgG
• 免疫原配列: (S-P-SP-M-P)
• NCBIアクセッション番号: NP_001781.2
• UniProtアクセッション番号: P30307
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer216)
• 遺伝子情報: human ... CDC25C(995)

詳細

免疫原

Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P), according to the protein CDC25C.

特徴および利点

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ターゲットの説明

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclinB-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiplealternatively spliced transcript variants of this gene have been described, however, the full-length nature of many ofthem is not known.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable