SAB4200651

Monoclonal Anti-Histone H3 (C-terminal) antibody produced in mouse

clone H6.10, purified from hybridoma cell culture

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: H6.10, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~14 kDa
• 化学種の反応性: chicken, human, monkey, hamster, canine
• 濃度: ~1 mg/mL
• テクニック: immunoblotting: 0.25-0.5 μg/mL using using histones isolated from human HeLa cells.; immunofluorescence: 5-10 μg/mL using using HeLa cells.
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... HIST1H3A(8350)

詳細

詳細

Histone cluster 1 H3A (HIST1H3A) belongs to the H3 histone family. The gene encoding it is localized on human chromosome 6.

Monoclonal Anti-Histone H3 (C-terminal) (mouse IgG1 isotype) is derived from the hybridoma H6.10 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a sequence at the C terminal region of human Histone H3, conjugated to KLH.

免疫原

a synthetic peptide corresponding to a sequence at the C terminal region of human Histone H3.

アプリケーション

Monoclonal Anti-Histone H3 (C-terminal) antibody has been used in

• immunoblotting
• immunofluorescence
• western blotting

生物化学的／生理学的作用

H3.1 (Histone 3-variant 1) is involved in gene silencing as well as gene activation. Histones H3 and H4 are the predominant histones subjected to extensive covalent modifications. Mutations in histone H3 were identified in various tumors.

Histone cluster 1 H3A (HIST1H3A) has been associated with DNA replication.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable