SAB4200471

Anti-SND1 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 別名: Anti-TDRD11, Anti-staphylococcal nuclease and tudor domain containing 1, p100
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~102 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: ~1.0 mg/mL
• テクニック: immunoprecipitation (IP): 1-2 μg using lysates of rat NRK cells.; indirect immunofluorescence: 2.5-5.0 μg/mL using human HeLa cells; western blot: 0.25-0.5 μg/mL using whole extracts of mouse NIH-3T3 cells.
• UniProtアクセッション番号: Q7KZF4
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SND1(27044) ; mouse ... Snd1(56463) ; rat ... Snd1(64635)

詳細

詳細

Staphylococcal nuclease and tudor domain containing 1 (SND1) protein contains five staphylococcal nuclease-like domains and a tudor-like domain. SND1 is a component of the RNA-induced silencing complex (RISC). This gene is highly conserved from yeast to human.

免疫原

peptide corresponding to the C-terminal region of human SND1 (GeneID: 27044), conjugated to KLH. The corresponding sequence is identical in mouse and rat.

アプリケーション

Anti-SND1 (C-terminal) antibody produced in rabbit has been used in immunoblotting, immunoprecipitation and immunofluorescence.

生物化学的／生理学的作用

Staphylococcal nuclease and tudor domain containing 1 (SND1) has been shown to be involved in the regulation of transcription and RNA biogenesis. It is known to interact with nucleic acids and proteins. SND1 promotes the breakdown of hyper-edited inosine-containing miRNA precursors. It modulates miRNA transcription and translation through RNA editing by ADAR (adenosine deaminase acting on RNA). Increased SND1 expression is seen in human colon cancer tissues and cell lines.

物理的形状

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable