SAB3501228

Anti-Avian Influenza A M2 antibody produced in rabbit

affinity isolated antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: liquid
• 化学種の反応性: influenza A virus (avian)
• 濃度: 1 mg/mL
• テクニック: ELISA: suitable
• アイソタイプ: IgG
• UniProtアクセッション番号: Q2L7I8
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Avian Influenza A M2 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments. It has been suggested as a target of neutralizing antibodies.

免疫原

M2 antibody was raised against a 13 amino acid synthetic peptide from amino terminus of H5N1 M2.The immunogen is located within the first 50 amino acids of Avian Influenza A M2.

アプリケーション

M2 antibody can be used for the detection of the M2 protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 mg/mL.

物理的形状

Supplied in PBS containing 0.02% sodium azide.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable