SAB3500065

Anti-Seasonal H1N1 Neuraminidase antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-Flu N1, Anti-Influenza N1, Anti-NA, Anti-Seasonal Influenza A (H1N1) Neuraminidase
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA (i)
• クローン: polyclonal
• 化学種の反応性: viral
• テクニック: indirect ELISA: suitable

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: viral
• テクニック: indirect ELISA: suitable
• NCBIアクセッション番号: ACA33620
• UniProtアクセッション番号: B1AGS8
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified

詳細

免疫原

Neuraminidase antibody was raised against a synthetic peptide from the seasonal influenza (H1N1) Neuraminidase protein. This antibody is a cognate pair with product SAB3500066.

特徴および利点

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ターゲットの説明

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States (2). The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic (3). Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin (4). The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups (5). This antibody is specific for Neuraminidase from the seasonal influenza (H1N1) and will not recognize the corresponding Neuraminidase sequence from the swine-origin influenza virus (A/California/14/2009 (H1N1)).

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500065.

物理的形状

約1 mg/mLのPBS (0.02％ アジ化ナトリウム含有)

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable