SAB1306537

ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 51896 Da
• 化学種の反応性: human, mouse
• テクニック: flow cytometry: 1:10-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:1000
• NCBIアクセッション番号: NP_003757.1
• UniProtアクセッション番号: Q14457
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BECN1(8678)

詳細

詳細

Beclin 1 (BECN1) is a tumor suppressor gene. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21.

アプリケーション

ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit has been used in Western blotting.

生物化学的／生理学的作用

Beclin 1 (BECN1) acts as an initiator of autophagy and is vital in the early stages of autophagosome formation. It has a role in various tumors and cancers. BECN1 is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking.

物理的形状

PBS（0.09％ （W/V）アジ化ナトリウム含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable