S9809

抗Sp1抗体 ウサギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• MDL番号: MFCD02097425
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 95-106 kDa
• 化学種の反応性: human
• テクニック: microarray: suitable; western blot: 1:100 using a nuclear extract from HeLa human epithelioid carcinoma cells
• UniProtアクセッション番号: P08047
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SP1(6667)

詳細

詳細

Sp1 (Simian virus 40 protein-1) is a ubiquitous sequence specific nuclear transcription factor that recognizes GGGGCGGGGC and related sequences (GC boxes) on numerous viral and cellular genes. The sequence specificity of DNA binding is conferred by three c-terminal Cys2His2-type zinc -fingers and its affinity is regulated by a different region. Sp1 is an abundant phosphorylated and O-glycosylated protein that is expressed in most cells in levels dependent on cell type and developmental stage. It is a member of a family comprising Sp1, Sp2, Sp3, Sp4 and at least twelve additional Sp1 like members.

免疫原

ヒトSp1のアミノ酸436-454 (N末端リジン付加) に相当する合成ペプチドのKLH結合体。

アプリケーション

Anti-Sp1 antibody produced in rabbit has been used in western blotting and immunoprecipitation.

生物化学的／生理学的作用

Sp1 (Simian virus 40 protein-1) has been implicated in maintenance of homeostasis and in cellular responsiveness to environmental changes. It mainly appears to be an activation transcription factor.

物理的形状

0.01 M PBS溶液(pH 7.4, 1%BSA, 15 mMアジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.