S9571

抗SUMO-2 ウサギ宿主抗体

~0.6 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: Anti-SMT3B, Anti-SMT3H2, Anti-Sentrin-2
• MDL番号: MFCD03455941
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~15 kDa
• 化学種の反応性: human
• 強化検証: recombinant expression; Learn more about Antibody Enhanced Validation
• 濃度: ~0.6 mg/mL
• テクニック: indirect immunofluorescence: 10-20 μg/mL using HeLa cells; western blot: 0.5-1 μg/mL using nuclear extract of HeLa cells or cell extract of HEK293-T cells transfected with human SUMO-2
• UniProtアクセッション番号: P61956
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SUMO2(6613) ; mouse ... Sumo2(170930)

詳細

詳細

Small ubiquitin-related modifier (SUMO-2) gene is mapped to human chromosome 17q25.1. Sumo-2 is related to SUMO-3 with a 86% sequence identity. It comprises a sumoylation motif at the residue lysine 11.

特異性

Anti-SUMO-2 recognizes human SUMO-2.

免疫原

synthetic peptide corresponding to amino acids 80-93 located at the C-terminal of human SUMO-2, conjugated to KLH. This sequence is identical in many species including rat, mouse, pig, and bovine SUMO-2 and is identical in human SUMO-3.

アプリケーション

Anti-SUMO-2 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

生物化学的／生理学的作用

Small ubiquitin-related modifier (SUMO-2) is essential for the cellular defense in hyperthermic cytotoxicity. Along with SUMO-3, SUMO2 is essential for cell survival post-heat shock. SUMO-2 has the ability to exist as self-modified polymers. SUMO-2 and SUMO-3 negatively regulate interferon induction.

物理的形状

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 1% bovien serum albumin and 15 mM sodium azide.

保管および安定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)