化学種の反応性
human
包装
kit of 96 wells (12 strips x 8 wells)
テクニック
ELISA: suitable
capture ELISA: suitable
入力
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.5 pg/mL
standard curve range: 4.1-1000 pg/mL
検出方法
colorimetric
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
human ... PPBP(5473)
詳細
Platelet-derived chemokine (C-X-C motif) ligand 7 (CXCL7), also known as neutrophil-activating protein-2 (NAP-2), is a member of a subset of seven chemokines. The protein is produced in platelets and its structure contains an N-terminal glutamate-leucine-arginine (ELR) motif. It acts as a ligand for the CXC chemokine receptor 2 (CXCR2). NAP-2 facilitates the migration of bone marrow mesenchymal stem cells (MSCs) to the injury site. In addition, it also aids in monocyte recruitment during atherogenesis. The Human NAP-2 enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants, and urine.
The Human NAP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human NAP-2 in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human NAP2
アプリケーション
Human NAP-2 / CXCL7 ELISA Kit has been used in enzyme-linked immunosorbent assay to quantitatively measure NAP-2/CXCL7 in serum samples of chronic myelomonocytic leukemia (CMML) patients.
その他情報
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
For research use only. Not for use in diagnostic procedures.
Please type the word sample in the text box provided for lot number.
For research use only. Not for use in diagnostic procedures.
シグナルワード
Warning
危険有害性情報
注意書き
危険有害性の分類
Met. Corr. 1
保管分類コード
8A - Combustible corrosive hazardous materials
適用法令
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Jan Code
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Qian Guo et al.
Oncology reports, 37(2), 1114-1122 (2016-12-14)
CXCL7 is an important chemoattractant cytokine, which signals through binding to its receptor CXCR2. Recent studies have demonstrated that the CXCL7/CXCR2 signaling plays a promoting role in several common malignancies, including lung, renal, colon, and breast cancer. However, the regulatory
Catarina R Almeida et al.
Stem cell reports, 6(4), 466-473 (2016-04-08)
Strategies for improved homing of mesenchymal stem cells (MSCs) to a place of injury are being sought and it has been shown that natural killer (NK) cells can stimulate MSC recruitment. Here, we studied the chemokines behind this recruitment. Assays
Thomas Baltus et al.
Journal of leukocyte biology, 78(2), 435-441 (2005-05-19)
Platelet-derived chemokines, such as regulated on activation, normal T expressed and secreted (RANTES; CC chemokine ligand 5), platelet factor 4 [PF4; CXC chemokine ligand 4 (CXCL4)], and epithelial neutrophil-activating protein 78 (ENA-78; CXCL5), or precursors, such as beta-thromboglobulin, which can
Wei Jiang et al.
Experimental and therapeutic medicine, 19(4), 2449-2456 (2020-04-08)
Overuse and misuse of antibiotics leads to antibiotic resistance which has become a significant public health concern. Klebsiella pneumoniae is the most common pathogenic bacteria underlying nosocomial infections due to the expression of virulence factors and occurrence of antibiotic resistance.
Kristen Meldi et al.
The Journal of clinical investigation, 125(5), 1857-1872 (2015-03-31)
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in genes encoding epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but response is highly variable, with few means to predict
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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