R4653

モノクロナール抗hnRNP-A2/B1 マウス宿主抗体

clone DP3B3, purified from hybridoma cell culture

• 別名: 抗不均一核リボ核タンパク質A2/B1抗体
• MDL番号: MFCD03845440
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: DP3B3, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~36 kDa
• 化学種の反応性: rat, human, bovine, hamster, monkey, chicken, mouse, canine
• テクニック: immunocytochemistry: suitable; immunoprecipitation (IP): suitable; microarray: suitable; western blot: 1-2 μg/mL using total cell extract from 293T cell line
• アイソタイプ: IgG2a
• UniProtアクセッション番号: P22626
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... HNRNPA2B1(3181) ; mouse ... Hnrnpa2b1(53379) ; rat ... Hnrnpa2b1(362361)

詳細

詳細

Monoclonal Anti-hnRNP-A2/B1 (mouse IgG2a isotype) is derived from the DP3B3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant human hnRNP-A2. hnRNP-A2/B1 proteins are located in the nucleus of most tissues cells. However, the hnRNP-A2 protein is found also in the cytoplasm of skin and esophagus cells. In rat brain, hnRNP-A2/B1 proteins are found in neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamin and the supraoptic nucleus of the hypothalamus.

免疫原

組み換えヒトhnRNP-A2。

アプリケーション

Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :

• enzyme linked immunosorbent assay (ELISA)
• immunoblotting
• immunoprecipitation
• immunocytochemistry

生物化学的／生理学的作用

In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).

物理的形状

0.01M PBS溶液(pH 7.4, 15mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable