Q0632

キナプリル 塩酸塩

≥98% (HPLC), solid

• 別名: (3S)-2-[(2S)-2-[[(1S)-1-(エトキシカルボニル)-3-フェニルプロピル]アミノ]-1-オキソプロピル]-1,2,3,4-テトラヒドロ-3-イソキノリンカルボン酸 塩酸塩
• 実験式（ヒル表記法）: C₂₅H₃₀N₂O₅ · HCl
• CAS番号: 82586-55-8
• 分子量: 474.98
• MDL番号: MFCD00889215
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823858
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 形状: solid
• 色: white
• 溶解性: H₂O: >10 mg/mL
• 保管温度: 2-8°C
• SMILES記法: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(O)=O
• InChI: 1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1
• InChI Key: IBBLRJGOOANPTQ-JKVLGAQCSA-N
• 遺伝子情報: human ... ACE(1636)

詳細

アプリケーション

Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.

生物化学的／生理学的作用

Quinapril has been studied to exhibit therapeutic effects against hypertension and congestive heart failure.

Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H361d,H372
• 注意書き: P202 - P260 - P264 - P280 - P308 + P313 - P405
• 危険有害性の分類: Repr. 2 - STOT RE 1
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)