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Merck

PRS4101

Sigma-Aldrich

Anti-Neuritin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

別名:

Anti-Cpg15, Anti-NRN1, Anti-Neuritin 1

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About This Item

UNSPSCコード:
12352203

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

predicted mol wt 16 kDa

化学種の反応性

mouse, human

テクニック

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... NRN1(51299)

詳細

Neuritin (NRN1) is a candidate plasticity associated gene, that is a member of the neurotrophic factor family. It is also known as CPG15. It is expressed in the liver, heart, lungs, skeletal muscle and other normal organs along with the nervous system. It is also expressed in gastric cancer tissues. It is mapped to chromosome 6p24-p2.

免疫原

a 20 amino acid peptide from near the center of human neuritin.

アプリケーション

Anti-Neuritin has been used in immunohistochemistry and western blotting.

生物化学的/生理学的作用

In gastric cancer treatment, neuritin (NRN1) serves as a potential target. It also participates in the pathogenesis of tumors. It plays a major role in the nervous system and on the migration, senescence, proliferation, and viability of stem cells.

関連事項

The action of this antibody can be blocked using blocking peptide SBP4101.

物理的形状

PBS溶液(0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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関連製品

製品番号
詳細
価格

保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Shuhei Kamada et al.
Frontiers in oncology, 11, 758503-758503 (2021-11-23)
Acquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently characterized that neuritogenesis-related protein neuritin 1 (NRN1) functions as
Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells
Wang X, et al.
Cellular & Molecular Biology Letters, 20(3), 466-474 (2015)
Overexpression of neuritin in gastric cancer
Yuan M, et al.
Oncology Letters, 10(6), 3832-3836 (2015)
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia
Chandler D, et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 153B(2), 428-437 (2010)
Ming Yuan et al.
Oncology letters, 10(6), 3832-3836 (2016-01-21)
The aim of the present study was to investigate the expression of neuritin in gastric cancer tissues, in order to explore the association between the expression of neuritin and the occurrence and development of gastric cancer. Tissue specimens were collected

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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