P7373

PAK7 Active human

≥75% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

• 別名: PAK5
• MDL番号: MFCD07371026
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• リコンビナント: expressed in E. coli
• 品質水準: 200
• アッセイ: ≥75% (SDS-PAGE)
• フォーム: buffered aqueous glycerol solution
• 比活性: 10 units/mg protein (Bradford)
• 分子量: protein apparent mol wt ~116 kDa by SDS-PAGE
• UniProtアクセッション番号: Q9P286
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... PAK7(57144)

詳細

生物化学的／生理学的作用

PAK7 is a PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus. PAK7 has been implicated in the regulation of cell morphology, motility and transformation. PAK7 is moderately expressed in adult and fetal whole brain and in all specific adult brain regions tested.

単位の定義

One unit will incorporate one nanomole of phosphate into the peptide substrate CKRPRAASFAE per minute at 30 °C and pH 7.2 using a final concentration of 50 μM [32P] ATP.

物理的形状

Solution in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)