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Merck

P0981

Sigma-Aldrich

Anti-Potassium Channel TASK-1 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.41
結合体:
unconjugated
application:
WB CL
クローン:
polyclonal
化学種の反応性:
human, rat
citations:
3
テクニック:
western blot (chemiluminescent): 1:200

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

lyophilized powder

化学種の反応性

human, rat

テクニック

western blot (chemiluminescent): 1:200

UniProtアクセッション番号

保管温度

−20°C

遺伝子情報

human ... KCNK3(3777)
mouse ... Kcnk3(16527)
rat ... Kcnk3(29553)

関連するカテゴリー

免疫原

synthetic peptide corresponding to amino acid residues 252-269 of human TASK-1 (with additional C-terminal cysteine). The epitope is highly conserved in mouse and rat TASK-1.

物理的形状

Lyophilized at ~0.6 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose, and 0.025% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

11 - Combustible Solids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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文書ライブラリにアクセスする

Sven G Meuth et al.
The Journal of biological chemistry, 283(21), 14559-14570 (2008-04-01)
Two major K(+) channels are expressed in T cells, (i) the voltage-dependent K(V)1.3 channel and (ii) the Ca(2+)-activated K(+) channel KCa 3.1 (IKCa channel). Both critically influence T cell effector functions in vitro and animal models in vivo. Here we
F Duprat et al.
The EMBO journal, 16(17), 5464-5471 (1997-10-06)
TASK is a new member of the recently recognized TWIK K+ channel family. This 395 amino acid polypeptide has four transmembrane segments and two P domains. In adult human, TASK transcripts are found in pancreas<placenta<brain<lung, prostate<heart, kidney<uterus, small intestine and
Alexandra Mant et al.
Channels (Austin, Tex.), 7(4), 288-302 (2013-06-29)
Acid-sensitive, two-pore domain potassium channels, K(2P)3.1 and K(2P)9.1, are implicated in cardiac and nervous tissue responses to hormones, neurotransmitters and drugs. K(2P)3.1 and K(2P)9.1 leak potassium from the cell at rest and directly impact membrane potential. Hence altering channel number
Constanze Schmidt et al.
Circulation, 132(2), 82-92 (2015-05-09)
Antiarrhythmic management of atrial fibrillation (AF) remains a major clinical challenge. Mechanism-based approaches to AF therapy are sought to increase effectiveness and to provide individualized patient care. K(2P)3.1 (TASK-1 [tandem of P domains in a weak inward-rectifying K+ channel-related acid-sensitive

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