MAK110

MTP Activity Assay Kit

Supplied by Roar Biomedical, Inc.

• 別名: MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
• UNSPSCコード: 12161503
• NACRES: NA.84

特性

• 使用法: sufficient for 100 fluorometric tests
• アプリケーション: pharmaceutical
• 検出方法: fluorometric
• 関連疾患: cardiovascular diseases
• 保管温度: 2-8°C
• 遺伝子情報: human ... MTTP(4547)

詳細

詳細

Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL). MTP is also necessary for assembly and secretion of chylomicrons by the intestine. This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.

アプリケーション

MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).

特徴および利点

Compatible with high-throughput handling systems.

適合性

Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.

原理

The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λ_Ex=465 nm/λ_Em=535 nm).

アナリシスノート

Learn more about Roar Assay Kits for Studies in Lipoprotein Metabolism.

安全性情報

• 保管分類コード: 10 - Combustible liquids