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由来生物
human
品質水準
リコンビナント
expressed in E. coli
アッセイ
≥97% (SDS-PAGE)
形状
lyophilized powder
有効性
10-20 ng/mL ED50
分子量
8.3 kDa
包装
pkg of 25 μg
テクニック
cell culture | mammalian: suitable
不純物
<0.1ng/mg
UniProtアクセッション番号
保管温度
−20°C
遺伝子情報
human ... CXCL11(6373)
生物化学的／生理学的作用
I-TAC (Interferon-inducible T-cell α chemoattractant) is a chemokine which participates in recruitment of inflammatory cell. It binds to receptor CXCR3 (C-X-C motif chemokine receptor 3). I-TAC is associated with the severity of dengue.
物理的形状
凍結乾燥品 (30%アセトニトリル, 0.1%TFA溶液, 1.25mg BSA含有)。
アナリシスノート
生物活性は、IL-2を添加して培養したヒトリンパ球の走化性誘導能により測定しています。
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
B P Hoh et al.
Human immunology, 76(6), 421-426 (2015-04-11)
Dengue causes significantly more human disease than any other arboviruses. It causes a spectrum of illness, ranging from mild self-limited fever, to severe and fatal dengue hemorrhagic fever, as evidenced by vascular leakage and multifactorial hemostatic abnormalities. There is no
D P Widney et al.
Journal of immunology (Baltimore, Md. : 1950), 164(12), 6322-6331 (2000-06-08)
A new murine chemokine was identified in a search for glucocorticoid-attenuated response genes induced in the lung during endotoxemia. The first 73 residues of the predicted mature peptide are 71% identical and 93% similar to human CXCL11/IFN-inducible T cell alpha
M R Rani et al.
The Journal of biological chemistry, 271(37), 22878-22884 (1996-09-13)
We report preliminary characterization of a gene designated beta-R1, which is selectively expressed in response to interferon beta (IFN-beta) compared with IFN-alpha. In human astrocytoma cells, beta-R1 was induced to an equivalent extent by 10 IU/mL IFN-beta or 2500 IU/mL
Y Luo et al.
Journal of neurovirology, 4(6), 575-585 (1999-03-05)
H174 is a new member of the CXC-chemokine family. A cDNA probe containing the entire H174 coding region recognized a predominant inducible transcript of approximately 1.5 kb expressed in interferon (IFN) activated astrocytoma and monocytic cell lines. H174 message can
R Krishnan Kutty et al.
Cytokine, 74(2), 335-338 (2015-04-22)
Dysfunction of the retinal pigment epithelium (RPE) resulting from chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD). RPE cells adjacent to drusen deposits in the AMD eye are known to contain CXCL11, a chemokine involved in
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