コンテンツへスキップ
Merck

GW21181

Sigma-Aldrich

Anti-VEGFR-2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

別名:

Anti-Vascular endothelial growth factor receptor 2

ログイン組織・契約価格を表示する


About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

chicken

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

交差性

rat, mouse, human

メーカー/製品名

Genway 15-288-21181

テクニック

immunohistochemistry: suitable
western blot: suitable

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... KDR(3791)

免疫原

Immunogen Sequence: GI # 9087218, sequence 51-119
Recombinant vascular endothelial growth factor receptor 2

アプリケーション

Anti-VEGFR-2 antibody produced in chicken is suitable for immunohistochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生物化学的/生理学的作用

Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase, VEGFR-2) is a VEGF receptor and is encoded by KDR gene in humans. It plays a crutial role in controlling endothelial trafficking activity and is involved in phosphotyrosine phosphatase 1b (PTP1b). PTP1b acts as a key regulator of endothelial VEGFR2 signaling and plays a critical role in regulation of the extent of vascular tree formation. VEGFR2 may be associated with gout and hyperuricaemia risks in Malays.

物理的形状

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

適切な製品が見つかりませんか。  

製品選択ツール.をお試しください

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

GW21181-50UG:
GW21181-VAR:
GW21181-BULK:


最新バージョンのいずれかを選択してください:

試験成績書(COA)

Lot/Batch Number

適切なバージョンが見つかりませんか。

特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Yap W K Roseline et al.
Malaysian journal of nutrition, 18(3), 307-317 (2012-12-01)
Gout and hyperuricaemia attributed to genetic and lifestyle factors have been associated with several chronic diseases. This study aimed to determine the association and interaction effects between vascular endothelial growth factor receptor-2 (VEGFR-2) gene polymorphisms (rs1870377 and rs2071559) and dietary
PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.
Lanahan AA, Lech D, Dubrac A, et al.
Circulation, 130(11), 902-909 (2014)
Giuseppe Di Stolfo et al.
Clinical hemorheology and microcirculation, 72(1), 23-38 (2018-10-16)
Carotid stenting stimulates intimal proliferation through platelet and stem cell activation. The aim of this study is to evaluate whether the administration before or after carotid stenting of clopidogrel loading dose may play a role on circulating endothelial progenitor cells
Soumaya Hachana et al.
British journal of pharmacology, 177(9), 1949-1966 (2019-12-29)
Age-related macular degeneration (AMD) is a complex neurodegenerative disease treated by anti-VEGF intravitreal injections. As inflammation is potentially involved in retinal degeneration, the pro-inflammatory kallikrein-kinin system is a possible alternative pharmacological target. Here, we investigated the effects of anti-VEGF and
G Ji et al.
The bone & joint journal, 101-B(7_Supple_C), 108-114 (2019-07-02)
It is increasingly appreciated that coordinated regulation of angiogenesis and osteogenesis is needed for bone formation. How this regulation is achieved during peri-implant bone healing, such as osseointegration, is largely unclear. This study examined the relationship between angiogenesis and osteogenesis

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)