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Key Documents

GE17-5317-02

Capto MMC

Cytiva 17-5317-02, pack of 100 mL

別名:

Capto MMC Resin, MMC Chromatography Resin

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About This Item

UNSPSCコード:
23151817
NACRES:
NA.56

詳細

Ion Exchanger Type (value)

包装

pack of 100 mL

メーカー/製品名

Cytiva 17-5317-02

マトリックス

highly cross-linked agarose

平均部品サイズ

75 μm (d50v)

cleaning in place

2-14

working range

2-12

キャパシティ

>45 mg binding capacity (BSA/ml medium at 30 mS/cm)

適合性

suitable for bioprocess medium

詳細

Capto MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges.

Capto MMC is a multimodal cation exchanger, belonging to the Capto family of BioProcess media for fast, efficient and cost-effective protein purification. Capto MMC combines agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges at both high and low ionic strengths.

The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.

Capto MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.
Dynamic binding capacity at 10% breakthrough as measured at a residence time of 2 min, 300 cm/h in a Tricorn 5/100 column with 10-cm bed height in 50 mM Sodium acetate, pH 4.75, 250 mM NaCl.

特徴および利点

  • Multimodal cation exchanger with a novel selectivity.
  • High dynamic binding capacity at high conductivity increases productivity
  • High-volume throughput cuts process times
  • Smaller unit operations give cost-effective processing and reduce investments

保管および安定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

アナリシスノート

この製品の分析証明書は、www.cytiva.com.

法的情報

Capto is a trademark of Cytiva

ピクトグラム

Flame

シグナルワード

Warning

危険有害性情報

保管分類コード

3 - Flammable liquids


試験成績書(COA)

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資料

Capto MMC is a multimodal cation exchanger with the properties of a weak cation exchanger. In addition to electrostatic interactions, the ligand structure provides for additional interaction modes such as hydrophobic interaction, hydrogen bonding, and thiophilic interaction.

Capto MMC is a multimodal cation exchanger with the properties of a weak cation exchanger. In addition to electrostatic interactions, the ligand structure provides for additional interaction modes such as hydrophobic interaction, hydrogen bonding, and thiophilic interaction.

This page describes the maintenance of media and storage conditions for multimodal chromatography using GE Healthcare products.

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