おすすめの製品
由来生物
goat
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
lyophilized powder
化学種の反応性
mouse
テクニック
immunohistochemistry: 5-15 μg/mL using cells and tissues
western blot: 0.1-0.2 μg/mL
UniProtアクセッション番号
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
mouse ... Ghr(14600)
詳細
イムノブロッティングによる抗体の交差反応性は、リコンビナントラットGHRで約50%、リコンビナントヒトGHRで20%です。
Growth Hormone Receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of intra- and intercellular signal transduction pathways.
免疫原
NSOで発現させたリコンビナントマウス成長ホルモンレセプタ-細胞外ドメインの精製物。
アプリケーション
Anti-Growth Hormone Receptor antibody produced in goat was used to study the protein and protein phosphorylation levels in rat primary hippocampal cultures using Li-cor Odyssey fluorescence technology.
生物化学的／生理学的作用
Growth hormone (GH) is secreted by the anterior pituitary and functions by binding specific growth hormone receptor (GHR). GH stimulates the secretion of insulin-like growth factor-1 that mediates some of its growth promoting actions. The activity of GH/GHR is important for normal physiology and aging processes.
物理的形状
凍結乾燥品 (PBS溶液, 5%トレハロ-ス含有, 0.2μmフィルタ-滅菌済み)。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
G8919-BULK:
G8919-100UG:
G8919-VAR:
G8919-100UG-PW:
Zhongbo Liu et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(2), 635-652 (2015-10-21)
Bone minerals are acquired during growth and are key determinants of adult skeletal health. During puberty, the serum levels of growth hormone (GH) and its downstream effector IGF-1 increase and play critical roles in bone acquisition. The goal of the
Andrzej Bartke et al.
Endokrynologia Polska, 64(1), 46-52 (2013-03-02)
Studies in mutant, gene knock-out and transgenic mice have demonstrated that growth hormone (GH) signalling has a major impact on ageing and longevity. Growth hormone-resistant and GH-deficient animals live much longer than their normal siblings, while transgenic mice overexpressing GH
Marie-Laure Baudet et al.
Proteomics, 8(2), 389-401 (2008-01-19)
The possible presence and action of growth hormone (GH) in the neural retina was investigated in newborn mice. The neural retina was found to be a site of GH gene expression, as GH mRNA was abundant in cells of the
Juan Ding et al.
Proteomics, 13(3-4), 674-685 (2012-09-29)
Growth hormone (GH) is a protein secreted by the anterior pituitary and circulates throughout the body to exert important actions on growth and metabolism. GH stimulates the secretion of insulin-like growth factor-I (IGF-I) that mediates some of the growth promoting
George A Garinis et al.
Nature cell biology, 11(5), 604-615 (2009-04-14)
The accumulation of stochastic DNA damage throughout an organism's lifespan is thought to contribute to ageing. Conversely, ageing seems to be phenotypically reproducible and regulated through genetic pathways such as the insulin-like growth factor-1 (IGF-1) and growth hormone (GH) receptors
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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