F1428

フェンバレレート

≥97%

• 別名: α-シアノ-3-フェノキシベンジル α-(4-クロロフェニル)­イソ­吉草酸
• 実験式（ヒル表記法）: C₂₅H₂₂ClNO₃
• CAS番号: 51630-58-1
• 分子量: 419.90
• Beilstein: 2025982
• MDL番号: MFCD00055324
• UNSPSCコード: 12352200
• PubChem Substance ID: 329799681
• NACRES: NA.77

特性

• 品質水準: 200
• アッセイ: ≥97%
• 保管温度: −20°C
• SMILES記法: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• InChI Key: NYPJDWWKZLNGGM-UHFFFAOYSA-N

詳細

詳細

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

アプリケーション

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

生物化学的／生理学的作用

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).

調製ノート

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H301,H315,H319,H335,H410
• 注意書き: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable