詳細
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製品種目
MISSION®
形状
lyophilized powder
esiRNA cDNA標的配列
CCTGCTACATTCCAGGCATTGTACTAAGTATGGGGAACCACAGAGAAGACATTCCCTCAGAAACTGCTGCAGTGCTTTCGCTTATCCCTACCTAAAAAACCGTCAATGTGAAATCATTTCCTTGATTATAACTATAATGATAATGGATTAGTTTATATAAACCTATGTTTAGACAAGTTCAAGACAAGCGTGTCTTTCTATAAAAAGTATTGAAAATGAAGGAAATGAGATCATGTTTCAATTTATTAAAGCAGGGAAGAGCGTTCTGTGCTTAGTTCGTGTCTAGGATTTGAGTGCCTTACTGAATGCATTTACCAGCAAACATGTAGCAATCTGTTCTCTCATTGTGATTGTGGAAGAAGCTCATGTAAAATGATAGTCATTAATGAGGAAGTATGGCGTGG
Ensembl |ヒトアクセッション番号
NCBIアクセッション番号
輸送温度
ambient
保管温度
−20°C
遺伝子情報
human ... FAM35A(54537) , FAM35A(54537)
関連するカテゴリー
詳細
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法的情報
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
10 - Combustible liquids
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Nature communications, 9(1), 3925-3925 (2018-09-27)
53BP1 with its downstream proteins, RIF1, PTIP and REV7, antagonizes BRCA1-dependent homologous recombination (HR) and promotes non-homologous end joining (NHEJ) in an unclear manner. Here we show that REV7 forms a complex with two proteins, FAM35A and C20ORF196. We demonstrate
Nature, 560(7716), 117-121 (2018-07-20)
53BP1 is a chromatin-binding protein that regulates the repair of DNA double-strand breaks by suppressing the nucleolytic resection of DNA termini1,2. This function of 53BP1 requires interactions with PTIP3 and RIF14-9, the latter of which recruits REV7 (also known as
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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