すべての画像(1)

主要文書

EHU092591

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human ATF3 (1)

ログイン組織・契約価格を表示する

すべての画像(1)

About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

おすすめの製品

Slide 1 of 10

1 of 10

Sigma-Aldrich

EHU097401

MISSION^® esiRNA

Millipore

E1014

Benzonase^® ヌクレアーゼ

Sigma-Aldrich

E8263

Benzonase^® ヌクレアーゼ, 超高純度

Millipore

70664

エンドヌクレアーゼ Serratia marcescens（セラチア菌）由来

SAFC

1.01695

エンドヌクレアーゼ Serratia marcescens（セラチア菌）由来

Sigma-Aldrich

EHU099831

MISSION^® esiRNA

Sigma-Aldrich

Z184985

Prescored ampules

Sigma-Aldrich

710857

塩化鉄(III) 溶液

Sigma-Aldrich

341273

Factor D, Human

Sigma-Aldrich

341262

Factor B, Human

詳細

品質水準

100

製品種目

MISSION^®

フォーム

lyophilized powder

esiRNA cDNA標的配列

TTTTTCTCAGATCTGGTTTCTAAGAGTTTTGGGGGGCGGGGCTGTCACCACGTGCAGTATCTCAAGATATTCAGGTGGCCAGAAGAGCTTGTCAGCAAGAGGAGGACAGAATTCTCCCAGCGTTAACACAAAATCCATGGGCAGTATGATGGCAGGTCCTCTGTTGCAAACTCAGTTCCAAAGTCACAGGAAGAAAGCAGAAAGTTCAACTTCCAAAGGGTTAGGACTCTCCACTCAATGTCTTAGGTCAGGAGTTGTGTCTAGGCTGGAAGAGCCAAAGAATATTCCATTTTCCTTTCCTTGTGGTTGAAAACCACAGTCAGTGGAGAGATGTTTGGAAACCACAGTCAGTGGAGCCTGGGTGGTACCCAGGCTTTAGCATTATTGGATGTCAATAGCA

Ensembl |ヒトアクセッション番号

ENSG00000162772

NCBIアクセッション番号

NM_001040619

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... ATF3(467) , ATF3(467)

詳細

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

適切な製品が見つかりませんか。

製品選択ツール.をお試しください

保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number

適切なバージョンが見つかりませんか。

特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

COAを検索

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Nicorandil prevents doxorubicin-induced human umbilical vein endothelial cell apoptosis.

Chun-Chao Chen et al.

European journal of pharmacology, 859, 172542-172542 (2019-07-19)

Nicorandil is an adenosine triphosphate-sensitive potassium channel opener with additional antioxidant properties. Doxorubicin (DOX) is an anticancer drug that exerts oxidation-mediated adverse cardiovascular effects. This study examined the effects of nicorandil on DOX-induced cytotoxicity in human umbilical vein endothelial cells

Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells.

Shunyan Weng et al.

BMC gastroenterology, 16, 25-25 (2016-02-27)

Hepatocellular carcinoma (HCC) is one of most common and aggressive human malignancies in the world, especially, in eastern Asia, and its mortality is very high at any phase. We want to investigate mechanism of niclosamide inducing cell apoptosis in HCC.

Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.

Siqi Ma et al.

International journal of molecular medicine, 35(6), 1561-1573 (2015-04-16)

Glioblastomas are highly malignant gliomas that are extremely invasive with high rates of recurrence and mortality. It has been reported that activating transcription factor 3 (ATF3) is expressed in elevated levels in multiple malignant tumors. The purpose of this study

Activating transcription factor 3 promotes intestinal epithelial cell apoptosis in Crohn's disease.

Liugen Gu et al.

Pathology, research and practice, 214(6), 862-870 (2018-05-03)

Intestinal epithelial cell (IEC) apoptosis plays a vital role in the pathogenesis of Crohn's disease (CD), which is an inflammatory bowel disease (IBD). Activating transcription factor 3 (ATF3) modulates apoptosis under stress via regulating the p53 pathway. However, the expression

Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy.

Genaro Hernandez et al.

Science translational medicine, 12(525) (2020-01-10)

The exocrine pancreas expresses the highest concentrations of fibroblast growth factor 21 (FGF21) in the body, where it maintains acinar cell proteostasis. Here, we showed in both mice and humans that acute and chronic pancreatitis is associated with a loss

主要文書

MISSION^® esiRNA