C9672

モノクロナール抗神経細胞接着分子 マウス宿主抗体

clone NCAM-0B11, ascites fluid

• 別名: 抗CD56-CY抗体, 抗NCAM抗体
• MDL番号: MFCD00164707
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: ascites fluid
• 抗体製品タイプ: primary antibodies
• クローン: NCAM-0B11, monoclonal
• 分子量: antigen 140-180 kDa
• 含みます: 15 mM sodium azide
• 化学種の反応性: rat, human
• テクニック: immunocytochemistry: suitable using cells and tissues; western blot: 1:100 using a freshly prepared extract from newborn and adult rat brain, or rat cerebral cortex extract
• アイソタイプ: IgG1
• UniProtアクセッション番号: O15394; P13591
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NCAM1(4684) , NCAM2(4685) ; rat ... Ncam1(24586) , Ncam2(288280)

詳細

詳細

Monoclonal Anti-N-CAM (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Neural cell adhesion molecule (N-CAM), the best characterized CAM, exists in adult brain. It belongs to the family of sialoglycoproteins, which arise from alternative splicing of mRNA transcribed from a single gene. Immunocytochemical data indicate that in the adult, N-CAM is expressed mainly in cells of the nervous system. There are indications that N-CAM may also be expressed by non-neural cells in the adult, as it has been found in studies of various embryonic developmental stages.

Mouse monoclonal clone NCAM-0B11 anti-Neural Cell Adhesion Molecule antibody localizes the high molecular weight isoform of N-CAM (neural cell adhesion molecule) in human and several other mammalian species. The antibody shows a strong reaction to N-CAM A/N-CAM 180, however it also recognizes N-CAM B/N-CAM 140. In an immunoblot, the product reacts with polysialated N-CAM in embryonic material. Breakdown products of N-CAM may be stained; they appear as bands lower than 100 kD on the immunoblot.

免疫原

E17ラット前脳由来の成長円錐濃縮形質膜画分。

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (3 papers)

Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse has been used in:

• Immunofluorescence
• Immunohistochemistry
• Immunoblotting

生物化学的／生理学的作用

Neural cell adhesion molecule (N-CAM) are believed to be involved in cell-cell interactions and probably play an important role in embryogenesis and development.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable