C0867

抗CRTH2 (GRP44) ウサギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• 別名: 抗G-タンパク質共役型レセプター44(推定)抗体, 抗TH2細胞発現走化性因子レセプター相同体抗体
• MDL番号: MFCD08064414
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~43 kDa by calculation
• 化学種の反応性: rat, mouse, human
• テクニック: western blot: 1:500-1:1,000 using CRTH2-transfected Jurkat cells
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... GPR44(11251) ; mouse ... Gpr44(14764) ; rat ... Gpr44(309212)

詳細

免疫原

ヒトCRTH2 (GRP44)タンパク質のC末端近傍(アミノ酸329-348)に相当するペプチド。

アプリケーション

Anti-CRTH2 (GRP44) antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1,000 using CRTH2- transfected Jurkat cells.

生物化学的／生理学的作用

CRTH2 (chemoattractant receptor-homologous molecule), is known as the putative G protein-coupled receptor (GP44), is expressed on T helper 2 (Th2) cells. It is also referred as DP2, DL1R and CD294. It′s a human protein and belongs to G protein-coupled leukocyte chemo attractant receptor family. It is not expressed on human amniocytes or myocytes. On activation of CRTH2, PGD(2) induces human osteoclast apoptosis and the apoptosis intrinsic pathway. CRTH2, CD4 and T cells all together may be involved in the pathogenesis of IgG4-related Lacrimal gland enlargement (LGE) causing Mikulicz′s disease (MD).

物理的形状

PBS溶液 (0.02%アジ化ナトリウム含有, 抗体濃度 1mg/mL)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable