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Key Documents

安全性情報

B6901

Sigma-Aldrich

モノクローナル抗ウシIgG抗体 マウス宿主抗体

clone BG-18, ascites fluid

別名:

モノクローナル抗ウシIgG抗体

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

mouse

結合体

unconjugated

抗体製品の状態

ascites fluid

抗体製品タイプ

secondary antibodies

クローン

BG-18, monoclonal

含みます

15 mM sodium azide

化学種の反応性

bovine (non-reactive to IgM)

以下との反応禁止

pig, human, rabbit, sheep, cat, guinea pig, canine, horse, goat

テクニック

dot blot: suitable
indirect ELISA: 1:1000

アイソタイプ

IgG1

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

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詳細

The antibody reacts with an epitope on both bovine IgG1 and IgG2 in their native form. The antibody shows no reaction with the epitope after denaturation and reduction.
The antibody reacts with an epitope on both bovine IgG1 and IgG2 in their native form. The antibody shows no reaction with the epitope after denaturation and reduction. IgG (immunoglobulin G) contributes to 10–20% of plasma protein and is regarded as one of the most predominant serum protein. It consists of four subclasses: IgG1, IgG2, IgG3 and IgG4. The IgG structure possesses four polypeptide chains containing two identical γ heavy (H) chains and two identical γ or γ light (L) chains of 50 kDa and 25 kDa, respectively.

特異性

bovine IgG1 and IgG2

免疫原

Purified bovine IgG

アプリケーション

Monoclonal Anti-Bovine IgG antibody has been used in indirect immunoperoxidase staining.
Monoclonal Anti-Bovine IgG antibody produced in mouse is suitable for ELISA at a working dilution of 1:20,000. It may be used for immunohistochemistry of formalin-fixed, paraffin-embedded sections at a dilution of 1:1000. Monoclonal Anti-Bovine IgG antibody produced in mouse was used as an isotype control in ChIP assay.

生物化学的/生理学的作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

物理的形状

Ascites fluid containing 0.1% sodium azide

保管および安定性

For continuous use, store at 2-8°C. For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

B6901-.2ML:
B6901-.5ML:
B6901-BULK:
B6901-VAR:


試験成績書(COA)

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Histological and Immunohistochemical Studies on the Furstenberg's Rosette in Cows.
Asti R N, et al.
Kafkas U?niversitesi veteriner faku?ltesi dergisi, 17(2), 520-520 (2011)
Behnaz Heydarchi et al.
mAbs, 9(3), 550-566 (2016-12-21)
We isolated HIV-1 Envelope (Env)-specific memory B cells from a cow that had developed high titer polyclonal immunoglobulin G (IgG) with broad neutralizing activity after a long duration vaccination with HIV-1AD8 Env gp140 trimers. We cloned the bovine IgG matched
Clare F J Grant et al.
Journal of virology, 91(9) (2017-02-24)
Foot-and-mouth disease virus (FMDV) is a highly contagious viral disease. Antibodies are pivotal in providing protection against FMDV infection. Serological protection against one FMDV serotype does not confer interserotype protection. However, some historical data have shown that interserotype protection can
Ulrike I Mödder et al.
The Journal of biological chemistry, 284(28), 18767-18777 (2009-05-09)
Both estrogen receptor (ER) and peroxisome proliferator-activated receptor gamma (PPARgamma) regulate bone metabolism, and because steroid receptor coactivator (SRC)-2 (TIF-2) enhances ER and PPARgamma activity, we examined the consequences of deletion of SRC-2 on bone using SRC-2 knock out (KO)
J Phillips et al.
Cytotherapy, 3(3), 233-242 (2002-08-13)
CAMPATH-1 Abs have been used for T-cell depletion in stem-cell transplantation since the early 1980s. During that time there has been substantial progress in manufacturing techniques and quality control procedures. This article summarizes the methods used to produce the Abs

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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