A9396

アデノシン 2′-一リン酸

from yeast

• 別名: 2′-AMP, 2′-アデニル酸
• 実験式（ヒル表記法）: C₁₀H₁₄N₅O₇P
• CAS番号: 130-49-4
• 分子量: 347.22
• UNSPSCコード: 41106305
• eCl@ss: 32160414
• PubChem Substance ID: 24891443
• NACRES: NA.51

特性

• 由来生物: yeast
• 品質水準: 200
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 溶解性: 1 N NH₄OH: 50 mg/mL, clear, colorless to faintly yellow
• 保管温度: −20°C
• SMILES記法: NC1=NC=NC2=C1N=CN2[C@H]3[C@H](OP(O)(O)=O)[C@H](O)[C@@H](CO)O3.[H]O[H].NC4=NC=NC5=C4N=CN5[C@H]6[C@H](OP(O)(O)=O)[C@H](O)[C@@H](CO)O6
• InChI: 1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
• InChI Key: QDFHPFSBQFLLSW-KQYNXXCUSA-N

詳細

詳細

Adenosine 2′-monophosphate (2’-AMP) is an adenine nucleotide having single phosphate group esterified to the sugar moiety in the 2′-position.

アプリケーション

Adenosine 2′-monophosphate (2′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP. 2′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′-AMP is used in the synthesis of a new photoaffinity lable for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase. 2′,3′-cAMP and 2′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

生物化学的／生理学的作用

AMP serves as a key component of several compounds, including coenzyme A, which plays an essential role in energy metabolism, as well as certain key redox cofactors such as NAD⁺, NADP⁺, and FAD. Furthermore, AMP is one of the key components of RNA, which is essential for protein synthesis and other biological processes in cells.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)