74817

FITC-CM-Dextran

average mol wt 150,000

• 別名: FITC-CM-Dextran 150, Fluorescein isothiocyanate–Carboxymethyl–Dextran
• UNSPSCコード: 12352108
• NACRES: NA.32

特性

• 由来生物: synthetic
• 品質水準: 100
• 結合体: FITC conjugate
• フォーム: powder or crystals
• 分子量: average mol wt 150,000
• 組成: carboxymethyl content, 3-7%
• 標識化の程度: 0.001-0.020 mol FITCmol glucose
• 蛍光検出: λ_ex 493 nm; λ_em 517 nm±5 nm in 0.1 M Tris pH 8.0

詳細

詳細

FITC-CM-Dextran, also known as Fluorescein isothiocyanate–Carboxymethyl–Dextran, is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. FITC-CM-Dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform.

FITC-CM-Dextran is manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali, whereby O-carboxymethyl groups are introduced along the dextran chain.

アプリケーション

FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative charge.

It is also a suitable molecule to be used in encapsulation studies for polymersomal drug delivery systems or Ps DDS . FITC-CM-Dextran is a biocompatible molecule used as a starting material in several pharmaceutical and diagnostic applications.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable