477R-1

MAGEC2 (EP405) Rabbit Monoclonal Primary Antibody

• 別名: Melanoma-associated antigen C2
• UNSPSCコード: 12352203
• クローン: EP405, monoclonal
• application: IHC (p)
• 化学種の反応性: human
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:50 (concentrated)
• citations: 7

特性

• 由来生物: rabbit
• 品質水準: 100; 500
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: EP405, monoclonal
• 詳細: For In Vitro Diagnostic Use in Select Regions
• フォーム: buffered aqueous solution
• 化学種の反応性: human
• 包装: vial of 0.1 mL concentrate (477R-14); vial of 0.1 mL concentrate Research Use Only (477R-14-RUO); vial of 0.5 mL concentrate (477R-15); vial of 1.0 mL concentrate (477R-16); vial of 1.0 mL concentrate Research Use Only (477R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (477R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (477R-17); vial of 7.0 mL pre-dilute ready-to-use (477R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (477R-18-RUO)
• メーカー／製品名: Cell Marque^™
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:50 (concentrated)
• アイソタイプ: IgG
• コントロール: seminoma
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 視覚化: nuclear

詳細

詳細

Melanoma-associated antigen C2 (MAGEC2), encoded by the testis cancer gene CT10, belongs to a family of proteins that bind E3 RING ubiquitin ligases via a common MAGE homology domain.^1-3 The MAGE-RING complexes that are formed enhance the activity of the ubiquitin ligase binding partners. In vitro studies suggest that MAGEC2, which binds to TRIM28, is involved in tumorigenesis through the increased degradation of p53.⁴ In germ cell tumors, aberrant expression of MAGEC2 is exhibited in seminomas, but is absent in yolk sac tumor and embryonal carcinoma.^5-7

品質

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

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その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable