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Key Documents

384R-1

Sigma-Aldrich

SATB2 (EP281) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSCコード:
12352200
NACRES:
NA.41

由来生物

rabbit

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

EP281, monoclonal

詳細

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (384R-14)
vial of 0.5 mL concentrate (384R-15)
bottle of 1.0 mL predilute (384R-17)
vial of 1.0 mL concentrate (384R-16)
bottle of 7.0 mL predilute (384R-18)

メーカー／製品名

Cell Marque™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

アイソタイプ

IgG

コントロール

colon adenocarcinoma

輸送温度

wet ice

保管温度

2-8°C

視覚化

nuclear

遺伝子情報

human ... SATB2(23314)

関連するカテゴリー

詳細

Special AT-rich sequence-binding protein 2 (SATB2) is a marker that functions as a nuclear matrix-associated transcription factor that has been shown to identify colorectal carcinomas, including poorly differentiated colorectal carcinomas and metastases. Adenocarcinomasincluding breast, lung, and ovary may express SATB2 at lower frequencies.1 Therefore, SATB2 is useful for identifying a carcinoma of colorectal origin when identifying a cancer of unknown primary.

品質


IVD
IVD
IVD
RUO

関連事項

SATB2 Positive Control Slides, Product No. 384S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Fan Lin et al.
Archives of pathology & laboratory medicine, 138(8), 1015-1026 (2014-01-21)
Distinction of medullary carcinoma of the large intestine from other cytokeratin (CK) 7⁻/CK20⁻ carcinomas can be challenging when working on a tumor of unknown primary because the majority of medullary carcinomas are negative for CK7, CK20, and CDX2. To investigate
Michelle Moh et al.
The American journal of surgical pathology, 40(3), 419-432 (2015-11-10)
The primary origin of some ovarian mucinous tumors may be challenging to determine, because some metastases of extraovarian origin may exhibit gross, microscopic, and immunohistochemical features that are shared by some primary ovarian mucinous tumors. Metastases of primary colorectal, appendiceal
Yi-Jun Zhang et al.
EBioMedicine, 28, 62-69 (2018-02-06)
SATB2 (Special AT-rich sequence-binding protein 2) has recently been shown to be a specific biomarker of colorectal cancer (CRC). The aim of this study was to investigate the diagnostic potential of SATB2 as a means of detecting a CRC origin
Kristina Magnusson et al.
The American journal of surgical pathology, 35(7), 937-948 (2011-06-17)
The special AT-rich sequence-binding protein 2 (SATB2), a nuclear matrix-associated transcription factor and epigenetic regulator, was identified as a tissue type-specific protein when screening protein expression patterns in human normal and cancer tissues using an antibody-based proteomics approach. In this

資料

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

関連コンテンツ

Diagnostic Immunohistochemistry Procedures

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

免疫組織染色

免疫組織染色（IHC）による診断と現代の臨床病理学におけるその重要性についての概略IHCと、がんの診断および感染症の検出におけるその役割についてご紹介します。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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