おすすめの製品
由来生物
mouse
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
MRQ-58, monoclonal
詳細
For In Vitro Diagnostic Use in Select Regions (See Chart)
フォーム
buffered aqueous solution
交差性
human
包装
vial of 0.1 mL concentrate (382M-14)
vial of 0.5 mL concentrate (382M-15)
bottle of 1.0 mL predilute (382M-17)
vial of 1.0 mL concentrate (382M-16)
bottle of 7.0 mL predilute (382M-18)
メーカー／製品名
Cell Marque®
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
アイソタイプ
IgG1
コントロール
mantle cell lymphoma
輸送温度
wet ice
保管温度
2-8°C
視覚化
nuclear
遺伝子情報
human ... SOX11(6664)
詳細
SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination. citation Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).
品質
 IVD |  IVD |  IVD |  RUO |
関連事項
SOX-11 Positive Control Slides, Product No. 382S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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試験成績書（COA）
Lot/Batch Number
Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives.
Itziar Salaverria et al.
Haematologica, 91(1), 11-16 (2006-01-26)
Bernd Weigle et al.
Oncology reports, 13(1), 139-144 (2004-12-08)
Malignant glioma comprises the majority of primary human brain tumors with 16,800 new cases reported each year in the USA. Its prognosis remains dismal despite numerous attempts to improve conventional therapeutic modalities. Therefore, much effort is devoted to the exploration
Tiemo Katzenberger et al.
British journal of haematology, 142(4), 538-550 (2008-06-20)
Mantle cell lymphoma (MCL) is an aggressive lymphoid tumour characterized by the translocation t(11;14)(q13;q32) and a poor clinical outcome (median survival: 3-4 years). Recent studies revealed that increased proliferation of the tumour cells and certain chromosomal aberrations, such as deletions
Weifen Zeng et al.
The American journal of surgical pathology, 36(2), 214-219 (2012-01-19)
SOX11 expression has been recently shown to be useful in the diagnosis of mantle cell lymphoma (MCL), including cyclin D1-negative MCL with typical morphology. We evaluated SOX11 expression pattern in B-cell non-Hodgkin lymphoma (B-NHL) subtypes to confirm specificity and used
Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas.
Iwona Wlodarska et al.
Blood, 111(12), 5683-5690 (2008-04-09)
The genetics of t(11;14)(q13;q32)/cyclin D1-negative mantle cell lymphoma (MCL) is poorly understood. We report here 8 MCL cases lacking t(11;14) or variant CCND1 rearrangement that showed expression of cyclin D1 (2 cases), D2 (2 cases), and D3 (3 cases). One
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