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Key Documents

340M-9

Sigma-Aldrich

Thyroglobulin (MRQ-41) Mouse Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

MRQ-41, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (340M-94)
vial of 0.5 mL concentrate (340M-95)
bottle of 1.0 mL predilute (340M-97)
vial of 1.0 mL concentrate (340M-96)
bottle of 7.0 mL predilute (340M-98)

メーカー/製品名

Cell Marque

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

アイソタイプ

IgG1

コントロール

thyroid

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic

遺伝子情報

human ... TG(7038)

詳細

Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Anti-Thyroglobulin, combined with TTF1 are demonstrable by immunohistochemistry assay in the majority of thyroid neoplasms. A panel of antibodies for Thyroglobulin, TTF1, CK-7, CK19, and CK20 is useful when thyroid is the possible primary site of a metastatic tumor.

品質


IVD

IVD

IVD

RUO

関連事項

Thyroglobulin Positive Control Slides, Product No. 340S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

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文書ライブラリにアクセスする

D Bellet et al.
The Journal of clinical endocrinology and metabolism, 56(3), 530-533 (1983-03-01)
Human thyroglobulin (Tg) was used as an antigen in the development of antibodies by the hybridoma technique. From four antibodies that bound more than 40% labeled Tg, two were characterized (182/E4 and 211/A5). They were both of the immunoglobulin G
P A Bejarano et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(3), 189-194 (2000-09-12)
Thyroid transcription factor-1 (TTF-1), a member of the NKx2 family of homeodomain transcription factors, is a mediator of thyroid-specific transcription of the thyroglobulin (TG) gene. The combined immunohistochemical profile of TTF-1, TG, cytokeratin 7 (CK7), and cytokeratin 20 (CK20) in
Clara S Heffess et al.
Cancer, 95(9), 1869-1878 (2002-10-31)
Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to

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