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主要文書

300M-1

Cytokeratin (OSCAR) Mouse Monoclonal Antibody

Name: Cytokeratin (OSCAR) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

UNSPSCコード:

12352203

NACRES:

NA.41

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Sigma-Aldrich

SAB4200719

Anti-Laminin antibody, Mouse monoclonal

由来生物

mouse

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

OSCAR, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

形状

buffered aqueous solution

化学種の反応性

human

包装

vial of 0.1 mL concentrate (300M-14)
vial of 0.5 mL concentrate (300M-15)
bottle of 1.0 mL predilute (300M-17)
vial of 1.0 mL concentrate (300M-16)
bottle of 7.0 mL predilute (300M-18)

メーカー／製品名

Cell Marque^™

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

アイソタイプ

IgG2a

コントロール

prostate

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic

遺伝子情報

human ... KRT1(3848)

詳細

Anti-cytokeratin (OSCAR) is well-suited to distinguish epithelial carcinoma from non-epithelial malignancies and is used to aid epithelial tumor classification. This antibody has been used to characterize the source of various neoplasms and to study the distribution of keratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

品質

IVD

RUO

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Lymph node micrometastasis and prognosis in patients with oesophageal squamous cell carcinoma.

F Sato et al.

The British journal of surgery, 88(3), 426-432 (2001-03-22)

The purpose of this study was to investigate whether the presence of lymph node micrometastasis in pathological lymph node-negative (pN0) oesophageal squamous cell carcinoma had prognostic value. Some 1840 lymph nodes were obtained from 50 patients with pN0 oesophageal squamous

OSCAR, a novel broad anti-cytokeratin antibody optimized for diagnostic immunohistochemistry

Gown, AM, Yaziji H, Barry TS, Hwang HC

United States and Canadian Academy of Pathology Annual Meeting, 2003 null

Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.

J E Lewis et al.

Human pathology, 28(6), 664-673 (1997-06-01)

Spindle cell carcinoma (SpCC) is uncommon, with a predilection for the upper aerodigestive tract. Its histogenesis has not been resolved, although most authors support the sarcomatoid carcinoma concept. Ploidy analysis and proliferation indices have not been reported for laryngeal SpCCs.

Frequency and clinical impact of lymph node micrometastasis and tumor cell microinvolvement in patients with adenocarcinoma of the esophagogastric junction.

J D Mueller et al.

Cancer, 89(9), 1874-1882 (2000-11-07)

Tumor involvement of regional lymph nodes has a crucial impact on the prognosis of patients with adenocarcinoma of the esophagogastric junction (AEG). Although additional tumor cell deposits can be detected by sensitive methods (e.g., immunohistochemistry and polymerase chain reaction), their

Spontaneous losses of control of cytokeratin gene expression in transformed, non-epithelial human cells occurring at different levels of regulation.

A C Knapp et al.

Cell, 59(1), 67-79 (1989-10-06)

Intermediate filaments (IFs) of the cytokeratin (CK) type are cytoskeletal elements typical for epithelial differentiation. However, in diverse transformed culture lines of non-epithelial origin, rare cells emerge spontaneously, which synthesize, in addition to their vimentin IFs, CKs 8 and 18.